The Hollow Fiber Infection Model: Principles and Practice 

An Untapped Resource for Antibiotic Development in the “Age of Resistance”

John J. S. Cadwell


Designed to overcome the shortcomings of animal- and one compartment pharmacodynamics/pharmacokinetic models, the hollow fiber infection model is a closed, bio-safe system. Within each module, thousands of semi-permeable tubular fibers retain microorganisms, bacteria, and cells while allowing smaller materials like glucose, metabolic waste, and drugs to flow freely. The hollow fiber infection model generates clinically relevant data not obtainable by other methods for both single and multiple drug applications. Learn about the important considerations for effective set up and installation with this white paper from FiberCell Systems.