Target Enrichment Panels for Capture-Based SNP Genotyping

Researchers use custom probes to efficiently sequence regions of interest.

Genotyping single nucleotide polymorphisms (SNPs) has revolutionized our understanding of human genetics. In addition, next generation sequencing (NGS) allows researchers to sequence beyond SNPs to detect multiple allelic sites, insertions, deletions, and other variants. NGS is flexible because researchers can design sequencing probes for specific genomic regions. Targeted sequencing of SNPs and surrounding areas can be problematic on a large scale; however new custom target enrichment panels efficiently and reliably capture and sequence regions of interest.

Download this application note from Twist Bioscience to learn about the performance of their Custom Target Enrichment Panels in capture-based SNP genotyping.