Cellular heterogeneity is a key contributor to biological complexity. However, its true extent—at gene and protein levels—is often masked by bulk techniques such as RNA sequencing or microarray analysis. Single cell sequencing technology allows researchers to go deeper. Instead of providing an average snapshot of cell populations, single cell approaches give researchers the ability to better characterize tissue heterogeneity, identify rare cell types, and dissect molecular mechanisms cell by cell.
Download this guide from 10x Genomics to explore what single cell resolution can achieve, and what options are currently available for researchers.