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Technical Note

Seeing Past the Debris: A Better Way to Count Nuclei 

An automated cell counter accurately analyzes nuclei isolated from tissue samples.


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Researchers performing single nuclear RNA-sequencing and ATAC-sequencing workflows need to reliably count their starting material. However, nuclei samples isolated from tissue can be clumpy and full of debris, which generates inconsistent results. An automated cell counter accurately measures acridine orange/propidium iodide-stained nuclei and distinguishes between nuclei, intact cells, and debris.

Download this technical note from DeNovix to learn how the CellDropTM Automated Cell Counter out-performs manual counting with trypan blue staining.