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Picking the Right CRISPR System

Examining the major differences between Cas9 and Cas12






Researchers use CRISPR gene editing technology for applications such as plant genome engineering, biosensing, genome screening, treating genetic diseases, and diagnosing infections. Much of this versatility comes from CRISPR-associated protein (Cas) proteins, which recognize and cut specific pieces of DNA. Cas9 is the best-known and most widely-used of the Cas proteins, but Cas12 has gathered interest for its potential use in diagnostics.

Download this application note from ERS Genomics to learn about the differences between Cas9 and Cas12 and how to select the appropriate Cas protein for one’s research needs.