Phenotyping the Tumor Microenvironment with Multiplex Immunohistochemistry

The tumor microenvironment (TME) is a complex and dynamic landscape. Cells within the TME interact to either stifle or promote cancer progression. Researchers analyze the TME to find novel cell phenotypes and disease mechanisms, develop targeted therapies, study drug efficacy, and plan patient treatments. Identifying biomarkers provides crucial information about tumor and immune cell status and their spatial arrangement. However, traditional TME analysis methods, such as flow cytometry, destroy tissue morphology to obtain single cell suspensions.

Download this poster from Ultivue to learn about

• The major cellular players in the TME
• How immunohistochemistry methods are non-destructive and capable of multiplexing
• Phenotyping TME cells with InSituPlex technology