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Identifying Neuroinflammatory Biomarkers of COVID-19

Functional proteomics detects elevated neuroinflammatory markers in patient plasma and cerebrospinal fluid

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Although it is primarily a respiratory illness, COVID-19 affects other organ systems such as the cardiovascular system and the central nervous system (CNS). The relationship between the SARS-CoV-2 virus and the CNS is unclear, but studies have shown that the SARS-CoV-2 virus can lead to systemic inflammation, including in the brain. Functional proteomics reveals the mechanisms driving neurological manifestations of COVID-19.

Download this research summary to find out how Shelli Farhadian and her team from the Yale School of Medicine used IsoPlexis’ highly multiplexed functional proteomics to identify elevated neuroinflammatory markers in a COVID-19 patient.