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Low-Abundance Serum Proteins as Biomarkers for Cardiovascular Disease

Using deoxyoligonucleotides to bind proteins with high sensitivity and specificity

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Many individuals with cardiovascular disease (CVD) do not present with any of the disorder’s classic risk factors. Circulating proteins are a promising source for CVD biomarkers to complement existing clinically-relevant indicators. These proteins are often released at the very onset of CVD, well before visible manifestations or symptoms. However, detecting them at these low concentrations is a challenge.

Download this white paper from SomaLogic to learn how the SomaScan® assay overcomes obstacles linked with other assays, including insufficient detection sensitivity, non-specificity, and cross-reactivity.