No tumor prevails on its own. Rather, every tumor needs a community to thrive. Indeed, surrounding any one solid tumor are blood vessels, lymphatics, and a diverse neighborhood of cellular and noncellular components that engage in dynamic and bi-directional interactions. As such, it is fitting to conceptualize the tumor microenvironment (TME) as a heterogeneous and evolving ecosystem. The complexity of the TME presents unique technical challenges for researchers. But reliable tools, advanced systems, and smarter workflows that support both deeper analyses and reproducible results are not out of reach.
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