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Detecting an Accessible Biomarker of Neurodegeneration

A sensitive, automated immunoassay measures neurofilament light from patient blood samples.





Neurodegenerative disorders are challenging to diagnose and monitor because the central nervous system is hard to access. To help patients, scientists hunt for noninvasive biomarkers of neuropathies. Neurofilament light (NF-L) is a biomarker for axonal damage in a number of disorders, including Alzheimer’s disease, Huntington’s disease, and multiple sclerosis, and is present in the blood, albeit at very low levels. Scientists rely on an automated microfluidic immunoassay to accurately measure this promising biomarker in patient blood samples.

Download this application note from ProteinSimple, a Bio-Techne brand, to learn how scientists measure a biomarker of neurodegeneration in patient blood.