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Designing CRISPR Screens for Efficient Gene Function Analysis

Discover tips and tricks to successfully perform custom CRISPR screens.



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CRISPR-based technology has revolutionized genetics research, and scientists across disciplines now use this genome editing tool to uncover gene function in various model systems. While CRISPR technology is relatively straightforward, many factors influence a large-scale CRISPR screen’s efficiency and success, and the work necessary to validate identified hits.

Download this ebook from The Scientist's Creative Services Team and Twist Bioscience to discover

  • Factors to consider when deciding on a custom versus genome-wide CRISPR screen
  • How to maintain sgRNA library uniformity
  • Technological advances to further increase CRISPR screen flexibility