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Controlling Host Cell Proteins in Drug Development

How scientists detect and manage host cell proteins in production workflows.




Host cell proteins (HCPs) are endogenous by-products of cell-based methods for biomanufacturing. While scientists take steps to remove HCPs, some may remain in the final product. This can have serious consequences for therapeutic biologics because most cellular production vehicles are potentially immunogenic.

Download this white paper from Cytiva to learn more about HCPs, how to detect them, and how to develop more robust HCP management strategies.