The Scientist Logo_white

Clarifying and Filtering Cells for Protein Purification

Cell filtration in a 24-well plate.



TS_PALL_Scientific Brief-473x360

Scientists largely use centrifugation and filtration to clarify complex cell cultures when recovering extracellular proteins, such as monoclonal antibodies (mAbs). However, these steps can be time-consuming and costly for labs growing their cultures in 24-well plates. Furthermore, this manual process produces significant variability.

Download this scientific brief from Pall Laboratory to learn about

  • An alternative to using centrifugation/filtration/flocculation to clarify and sterilize mammalian cell cultures
  • New 24-well clarification and sterile filtration plates, and a 24-well sterilization-only filter plate for recovering proteins present in supernatant