Clarifying and Filtering Cells for Protein Purification

Scientists largely use centrifugation and filtration to clarify complex cell cultures when recovering extracellular proteins, such as monoclonal antibodies (mAbs). However, these steps can be time-consuming and costly for labs growing their cultures in 24-well plates. Furthermore, this manual process produces significant variability.

Download this scientific brief from Pall Laboratory to learn about

• An alternative to using centrifugation/filtration/flocculation to clarify and sterilize mammalian cell cultures
• New 24-well clarification and sterile filtration plates, and a 24-well sterilization-only filter plate for recovering proteins present in supernatant