Characterizing the Tumor Microenvironment

The tumor microenvironment (TME) is comprised of an array of cell types, including immune and inflammatory cells, adipose cells, neuroendocrine cells, and cancer-associated fibroblasts. Additionally, blood and lymphatic vascular networks and extracellular matrix components create a diverse and multifaceted situation. Understanding how all of these elements interact requires the ability to distinguish individual cell types--something that is difficult to do using bulk cell approaches. Single cell gene expression analyses offer a high-resolution understanding of the TME.

Download this application note from 10x Genomics to learn how the Chromium Single Cell Immune Profiling Solution enables you to

• Obtain gene expression profiles and paired, full length, immune receptor sequences from the same cells 
• Characterize and differentiate all major tumor and non-tumor cells
• Identify clonal immune cell populations to understand the adaptive immune response