The Scientist Logo_white

Assigning Meaning: Genetic Variant Interpretation in Hereditary Cancer

Improving the reliability of genetic variant annotation and clinical interpretation




Genetic testing is an important tool for diagnosing and preventing hereditary cancers. Variant annotation helps scientists interpret the clinical significance of genetic variants detected by next-generation sequencing. Unreliable annotation systems can cause inter-laboratory classification differences and discrepancies in clinical decisions, underscoring the need for annotation systems that accurately convey variant data from diverse data sources.

Download this application note from Qiagen to learn how reliable variant annotation systems improve the accuracy of clinical decision making in hereditary cancer.