APPLICATION OF TruBIOME TO INCREASE MOUSE MODEL REPRODUCIBILITY

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The microbiome is the collection of bacteria, viruses, fungi, and protozoa that inhabit mammalian hosts. Determining how the microbiome impacts health has been of key focus in recent years. To date, research has demonstrated that the microbiome can influence the development of a multitude of diseases including, but not limited to, inflammatory bowel disease, cancer, autoimmune disorders, obesity, neurodegenerative diseases, and metabolic disorders. 

The mouse remains an indispensable research component of many scientists’ experimental repertoires. Mouse models allow for the opportunity to experimentally manipulate and control variables that cannot reasonably be accomplished in human trials. However, to date, there are limited options for researchers to control for the gut microbiome of their research mice.
 
With this application note from Taconic, learn about:
  • Microbiome effects on reproducibility and predictability
  • How TruBIOME™ provides researchers with a platform to evaluate microbiota compositions and control for microbiome-produced effects
  • Using TruBIOME in microbiome research
  • Generating and using custom microbiota mouse models