Advancing Neurodegenerative Disease Research

Neurodegenerative diseases are a collection of complex illnesses that manifest differently in each patient. They include Parkinson’s disease, Alzheimer’s disease, and amyotrophic lateral sclerosis, among others. Protein misfolding and aggregation is a hallmark of neurodegenerative disease; researchers are learning more detail about this process by analyzing molecular interactions and thermal stability.

Download this eBook from NanoTemper to learn how to

• Measure the physicochemical properties of alpha-synuclein aggregates associated with Parkinson’s disease
• Characterize interactions between small molecules and fibrils to develop early diagnostic tools
• Discover the molecular mechanism of zinc-induced protein aggregation
• Find a novel role for phosphorylated tau on amyloid-beta toxicity
• Reveal how a single point mutation affects the neuropathology of ataxia