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A Platform for Automated CRISPR-Based Microbial Genome Engineering

Discover how you can design and generate genomic edits to optimize heterologous protein expression and activity in E. coli.

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Heterologous protein expression in microbial hosts enables many molecular biology applications, including protein engineering, biologics production, and structure-function discovery research. Researchers can now use efficient CRISPR editing tools to edit heterologous proteins directly in the host genome and simultaneously optimize their expression. This facilitates systematic control of protein activity and more in-depth examination of sequence-function relationships.

Download this application note from Inscripta to discover how to perform highly multiplexed CRISPR editing using a digital genome engineering platform.