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APPLICATION NOTE

A New Way of Exploring Immunity

Linking highly multiplexed antigen recognition to immune repertoire and phenotype


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T cells are key components of the adaptive immune system. T cell receptors (TCRs) bind to antigens on the surface of other cells to initiate an immune response. Scientists do not fully understand how diverse TCRs bind to their target antigens; however, they can use single cell profiling methods to directly observe these complex cellular interactions.

Download this application note from 10x Genomics to learn how single cell profiling can be used to understand

  • T cell receptor binding specificities
  • Gene and cell surface protein expression
  • How the adaptive immune system responds to immune insults